0

The full content of Annals is available to subscribers

Subscribe/Learn More  >
Articles |

Survival with Systemic Sclerosis (Scleroderma): A Life-Table Analysis of Clinical and Demographic Factors in 309 Patients

THOMAS A. MEDSGER JR., M.D.; ALFONSE T. MASI, M.D., Dr. P.H., F.A.C.P.; GERALD P. RODNAN, M.D., F.A.C.P.; THOMAS G. BENEDEK, M.D., F.A.C.P.; and HARRY ROBINSON, D.Sc.
[+] Article and Author Information

This study was supported in part by grants AM-12049 and AM-05055 of the National Institutes of Arthritis and Metabolic Diseases, National Institutes of Health, Bethesda, Md.; a grant from the Scleroderma Society of the Arthritis Foundation, New York, N.Y.; grant RR-56 from the General Clinical Research Center; and by the RGK Foundation.

▸Requests for reprints should be addressed to Thomas A. Medsger, Jr., M.D., 985 Scaife Hall, University of Pittsburgh School of Medicine, Pittsburgh, Pa. 15213


Memphis, Tennessee; and Pittsburgh, Pennsylvania


Ann Intern Med. 1971;75(3):369-376. doi:10.7326/0003-4819-75-3-369
Text Size: A A A

A life-table analysis of survivorship with scleroderma was done, using 223 patients diagnosed in Pittsburgh, Pennsylvania, and 86 patients in Memphis, Tennessee. The demographic and clinical characteristics of the two series were similar, thus allowing for both comparison of the two groups and analysis of the total 309 patients. A follow-up during 1970 was successful in 94% of all patients. No difference in survival was found between the two patient groups, the combined 7-year cumulative survivorship being 35%. Significantly decreased survival was found in older patients of both series after allowance was made for the natural increase of mortality with age. Males had significantly worse survival than females. Negroes had significantly worse survival than whites during the first year of follow-up of all patients. When no internal organ involvement was detected at entry to study, the negro prognosis was significantly worse throughout a 7-year follow-up period. Renal, cardiac, and pulmonary involvement were each independently correlated with decreased survival.

Figures

Tables

References

Letters

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Comments

Submit a Comment
Submit a Comment

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.

Toolkit

Buy Now

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Advertisement
Related Articles
Related Point of Care
Topic Collections
PubMed Articles

Buy Now

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.
(Required)
(Required)