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Hepatitis-Associated Antigen and Hepatocellular Carcinoma in Taiwan

MYRON J. TONG, M.D., Ph.D.; SHIH-CHIEN SUN, M.D.; BERTON T. SCHAEFFER, M.D.; NAI-KWEI CHANG, M.D.; KWANG-JUEI LO, M.D.; and ROBERT L. PETERS, M.D.
[+] Article and Author Information

Opinions and assertions contained herein are those of the authors and are not to be construed as official or reflecting the views of the Navy Department or the Naval Service at large.

Supported by funds for Work Unit MR005.09.01-0114A from the Bureau of Medicine and Surgery, U. S. Navy, Bethesda, Md.

▸Requests for reprints should be addressed to Myron J. Tong, M.D., Los Angeles County-USC Medical Center, Box 784, 1200 N. State St., Los Angeles, Calif. 90033


Taipei, Taiwan, and Los Angeles, California


Ann Intern Med. 1971;75(5):687-691. doi:10.7326/0003-4819-75-5-687
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Serums from 55 patients with primary hepatocellular carcinoma were examined for the presence of hepatitis-associated antigen (HAA). Forty-four (80%) had the antigen in their serums; alpha fetoglobulins were detected in 32 of 55 serums analyzed (58%). One hundred and thirty-eight of 943 (14.6%) healthy Chinese control subjects with normal serum glutamic-pyruvic transaminase activity had HAA in their serums. There was no apparent correlation between the presence of alpha fetoglobulins and HAA positivity in patients with hepatocellular carcinoma.

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