The full content of Annals is available to subscribers

Subscribe/Learn More  >
Brief Communications |

Altered Peritoneal Permeability in Patients with Systemic Vasculitis

[+] Article, Author, and Disclosure Information

Presented in part at the Midwestern Section Meetings of the American Federation for Clinical Research, 5 November 1970, Chicago, Ill.

▸Requests for reprints should be addressed to Karl D. Nolph, M. D., Department of Medicine, Division of Nephrology, University of Missouri Medical Center, Columbia, Mo. 65201

Columbia, Missouri, and Washington, D.C.

Ann Intern Med. 1971;75(5):753-755. doi:10.7326/0003-4819-75-5-753
Text Size: A A A

Decreased peritoneal membrane permeability should impair the transperitoneal diffusion of larger molecular weight solutes more than that of smaller solutes during peritoneal dialysis. To see if systemic vascular disease produces such selective functional alterations in man, peritoneal clearances of urea (Curea), creatinine (Ccr) and urate (Curate) were measured in four patients with severe systemic vascular disease. Mean values for Curea, Ccr/Curea, and Curate/Curea in the study patients were significantly (P < 0.01) below values for these functions in the control group. The selective reductions in the clearances of higher molecular weight solutes suggest alterations of functional permeability of the peritoneal capillaries or mesothelium, or both, in patients with systemic vascular disease.





Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Submit a Comment/Letter
Submit a Comment/Letter

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.


Buy Now for $42.00

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Related Articles
Topic Collections
PubMed Articles
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.