The full content of Annals is available to subscribers

Subscribe/Learn More  >
Original Research |

Smoker's Wrinkles: A Study in the Epidemiology of "Crow's Feet"

[+] Article, Author, and Disclosure Information

▸Requests for reprints should be addressed to Harry W. Daniell, M.D, 2020 Court St., Redding, Calif. 96001

Redding, California

Ann Intern Med. 1971;75(6):873-880. doi:10.7326/0003-4819-75-6-873
Text Size: A A A

A simple method of grading the severity of facial skin wrinkling is described. It can be rapidly learned and easily used by untrained students. In a study of 1,104 subjects the severity of wrinkling correlated with a history of habitual cigarette smoking, after adjustment for age and outdoor exposure. The association between cigarette smoking and wrinkling was striking in both sexes soon after age 30, was related to the duration and intensity of cigarette smoking, and was more pronounced than was the association between wrinkling and admitted outdoor exposure. Smokers in the 40- to 49-year age group were as likely to be prominently wrinkled as nonsmokers who were 20 years older.


foot ; skin wrinkling





Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Submit a Comment/Letter
Submit a Comment/Letter

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.


Buy Now for $42.00

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Related Articles
Journal Club
Topic Collections
PubMed Articles
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.