The full content of Annals is available to subscribers

Subscribe/Learn More  >
Original Research |

Aortic Insufficiency in Bacterial Endocarditis

[+] Article, Author, and Disclosure Information

▸Requests for reprints should be addressed to C. Glenn Cobbs, M.D., Division of Infectious Diseases, The University of Alabama Medical Center, Birmingham, Ala. 35233

Birmingham, Alabama

Ann Intern Med. 1972;76(1):23-28. doi:10.7326/0003-4819-76-1-23
Text Size: A A A

The records of 28 patients with bacterial endocarditis and aortic valve insufficiency were studied to determine clinical indications for valve replacement before bacteriologic cure can be accomplished. The four patients who never developed heart failure did well with medical therapy alone. Seven of 11 patients with mild heart failure died suddenly during treatment. At autopsy four of these were found to have had myocardial infarctions, presumably embolic. Seven of eight patients with moderate or severe heart failure who were treated medically died, whereas four of five with severe heart failure who had aortic valve replacement survived. Patients with bacterial endocarditis and aortic insufficiency who have severe heart failure should have aortic valve replacement performed immediately. Early valve replacement should also be considered in patients with only mild heart failure because they appear to be at significant risk of sudden death from embolic myocardial infarction or arrhythmia.





Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Submit a Comment/Letter
Submit a Comment/Letter

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.


Buy Now for $42.00

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Related Articles
Topic Collections
PubMed Articles
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.