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Essential Athrombia: A Family Study

[+] Article, Author, and Disclosure Information

Dr. Goldman was supported in part by USPHS Training Grant CA-051126, National Cancer Institute, National Institutes of Health, Bethesda, Md. Dr. Aledort was supported in part by USPHS Grant HE-10905, National Heart Institute, National Institutes of Health, and by the Albert A. List, Frederick Machlin, Anna Ruth Lowenberg, and Helen B. Kuyler Funds.

▸Requests for reprints should be addressed to Louis M. Aledort, M.D., Mount Sinai School of Medicine, New York, N.Y. 10029

New York, New York

Ann Intern Med. 1972;76(2):269-273. doi:10.7326/0003-4819-76-2-269
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This is the first report of a family with essential athrombia, a qualitative platelet disorder characterized by a moderate hemorrhagic diathesis. Diagnostic laboratory variables include a prolonged bleeding time, normal clot retraction, normal platelet factor 3 activity, and abnormalities in platelet aggregation. This disorder appears to be transmitted as a dominant trait, either autosomal or sex-linked.


family study





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