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Identifying the Adrenal Lesion in Primary Aldosteronism

JAMES C. MELBY, M.D.
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University Hospital, Boston University Medical Center, Boston, Mass.


Ann Intern Med. 1972;76(6):1039-1041. doi:10.7326/0003-4819-76-6-1039
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Adrenal angiography has developed rapidly during the past 10 years. Selective catheterization of the arteries supplying the adrenals with injection of contrast materials offers the best chance to obtain radiographic evidence of cortisol or androgen-producing adenomas and of functioning and nonfunctioning primary adrenocortical neoplasms. Adrenal arteriography will also permit the recognition of bilateral adrenocortical hyperplasia associated with alterations in ACTH (adrenocorticotropic hormone) secretion. Both adrenal arteriography and venography are used to identify the presence of a pheochromocytoma.

Small avascular aldosterone-producing adenomas (Conn's syndrome) and bilateral adrenocortical hyperplasia (idiopathic aldosteronism) resulting in the syndrome of primary aldosteronism are less easily identified

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