0

The full content of Annals is available to subscribers

Subscribe/Learn More  >
Case Reports |

Fatal Immune Thrombocytopenia Induced by Ethchlorvynol

ERIC S. JACOBSON, M.D.
[+] Article and Author Information

▸Requests for reprints should be addressed to Eric S. Jacobson, M.D., Westside Neighborhood Health Center, 10th and Federal Blvds., Denver, Colo. 80204.


Denver, Colorado


Ann Intern Med. 1972;77(1):73-76. doi:10.7326/0003-4819-77-1-73
Text Size: A A A

A case of recurring fulminant thrombocytopenia is described. Three of the five documented thrombocytopenic episodes are known to have been preceded by ingestion of ethclorvynol. The last ingestion was followed by an episode that resulted in the death of the patient. Hematologic values were normal between episodes. Various drugs that appeared to be related temporally to the patient's crises were screened for antiplatelet activity in vitro in the presence of the patient's serum. Ethchlorvynol inhibited clot retraction; no other agent had this effect. The author concludes that the thrombocytopenia was induced by this drug. This is believed to be the first case of thrombocytopenia to have been induced by ethchlorvynol.

Figures

Tables

References

Letters

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Comments

Submit a Comment
Submit a Comment

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.

Toolkit

Buy Now

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Advertisement
Related Articles
Related Point of Care
Topic Collections
PubMed Articles

Buy Now

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.
(Required)
(Required)