The full content of Annals is available to subscribers

Subscribe/Learn More  >
Brief Communications |

Megaloblastic Anemia Associated with Long-Term Tetracycline Therapy: Report of a Case

[+] Article, Author, and Disclosure Information

▸Requests for reprints should be addressed to Carroll C. Jones, M.D., 4023 Woodlawn, Pasadena, TX 77504.

Pasadena, Texas

Ann Intern Med. 1973;78(6):910-912. doi:10.7326/0003-4819-78-6-910
Text Size: A A A

An 18-year-old woman developed a sore mouth and a megaloblastic anemia while treated with tetracycline, 500 mg daily, for 3 years. Folate deficiency was found, and the anemia responded promptly to oral folic acid therapy. She had no evidence of vitamin B12 malabsorption and no history or clinical findings suggesting dietary lack of folate, malabsorption syndrome, increased folate requirements, or offending drug intake other than tetracycline. All possible tests for an occult malabsorption were not done.





Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Submit a Comment/Letter
Submit a Comment/Letter

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.


Buy Now for $42.00

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Related Articles
Topic Collections
PubMed Articles
Tropical sprue: revisited. J Pak Med Assoc 2004;54(3):133-4.
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.