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A Magnesium-Deficient Patient Presenting with Hypocalcemia and Hyperphosphatemia

[+] Article, Author, and Disclosure Information

Grant support: research grant RR00044, Division of Research Facilities and Resources, National Institutes of Health, U.S. Public Health Service.

▸Requests for reprints should be addressed to Christine Waterhouse, M.D., Department of Medicine, University of Rochester Medical Center, 260 Crittenden Blvd., Rochester, NY 14642.

Ann Intern Med. 1973;79(1):76-79. doi:10.7326/0003-4819-79-1-76
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A patient with hypomagnesemia caused by chronic alcoholism presented with tetany, hypocalcemia, and hyperphosphatemia. The biochemical abnormality was associated with refractory hypokalemia and was readily corrected by oral administration of magnesium hydroxide (milk of magnesia). It is suggested that magnesium deficiency be considered in patients with hypocalcemia and hyperphosphatemia, in addition to the classic differential diagnosis of hypoparathyroidism, pseudohypoparathyroidism and renal failure.





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