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Tachycardia-Aggravated Heart Disease

[+] Article, Author, and Disclosure Information

Grant support: HE-5786, HL-5035, HE-5546, HL-5968, and Program Project Award 1 PO1 HE-11504, National Heart and Lung Institute; and the Central Ohio Chapter of the American Heart Association. Dr. Engel was a Postdoctoral Trainee for the National Heart and Lung Institute.

▸Requests for reprints should be addressed to Stephen F. Schaal, M.D., Ohio State University, College of Medicine, Room 669, Means Hall, 466 W. 10th Ave., Columbus, OH 43210.

Columbus, Ohio

Ann Intern Med. 1974;80(3):384-388. doi:10.7326/0003-4819-80-3-384
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A woman with chronic sinoatrial tachycardia developed ventricular dysfunction 9 years after the onset of the tachycardia. Her history suggests that the myocardial contractile alterations may be a result rather than a cause of tachycardia. The cause of the tachycardia was not defined despite unique responses to electrophysiologic tests. Despite severely altered ventricular function, beta-adrenergic blockade markedly improved symptoms and hemodynamics.





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