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Disseminated Intravascular Coagulation During Heparin Therapy

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Grant support: research grant HL01601, National Heart and Lung Institute, National Institutes of Health.

▸Requests for reprints should be addressed to William R. Bell, M.D., The Johns Hopkins University Hospital, Hematology Division, Blalock 1002, 601 N. Broadway, Baltimore MD 21205.

Baltimore, Maryland

Ann Intern Med. 1974;80(4):477-481. doi:10.7326/0003-4819-80-4-477
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Two patients receiving intravenous heparin for pulmonary emboli developed disseminated intravascular coagulation during therapy. Both patients were receiving adequate anticoagulation before the onset of this syndrome. Mechanisms that might cause or prolong disseminated intravascular coagulation during heparin therapy are proposed.





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