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Renal Lithiasis in Gastrointestinal Disease

GEORGE N. AAGAARD, M.D.
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Subcommittee on Hospital-Based Education in Therapeutics, American Society for Clinical Pharmacolgy and Therapeutics, Seattle, Washington


Ann Intern Med. 1974;80(4):550. doi:10.7326/0003-4819-80-4-550_1
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Patients with various gastrointestinal diseases have an increased likelihood of developing renal stones either because [1] the primary disease process adversely affects urine composition and gastrointestinal function (hyperparathyroidism), [2] the treatment of the gastrointestinal disease leads to increased intake of material that is potentially precipitable in the urinary tract (treatment of peptic ulcer with calcium-containing antacids) (1), or [3] the gastrointestinal disease secondly leads to alterations in the quantity and composition of the urine.

In the past 10 years several studies have suggested that there is an increased incidence of renal stones in patients with inflammatory bowel disease, particularly those

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