The full content of Annals is available to subscribers

Subscribe/Learn More  >
Diagnosis and Treatment |

Chemoprophylaxis of Malaria for Travelers

[+] Article, Author, and Disclosure Information

▸Requests for reprints should be addressed to Elizabeth Barrett-Connor, M.D., Department of Community Medicine, Basic Science Bldg., School of Medicine, University of California, San Diego, La Jolla, CA 92037.

Ann Intern Med. 1974;81(2):219-224. doi:10.7326/0003-4819-81-2-219
Text Size: A A A

Physicians advising travelers going to parts of the world where malaria transmission occurs should recommend antimalarial prophylaxis. Chloroquine is the most reliable prophylactic agent affording prophylactic suppressive cure of all sensitive strains of falciparum malaria and suppression with occasional cure of other human malarias. A 14-day course of primaquine after the last exposure affords prophylactic radical cure of malarias with secondary exoerythrocytic cycles. A weekly combination of chloroquine and primaquine is equally effective if continued for 2 months after exposure, but is unnecessary for travelers visiting areas with chloroquine-sensitive malaria. Currently, the best prophylaxis for chloroquine-resistant falciparum malaria is weekly chloroquine and primaquine and daily dapsone. Travelers should be informed about simple precautions against mosquito bites and should advise their physician of the possibility of malaria if they become ill after they return.





Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Submit a Comment/Letter
Submit a Comment/Letter

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.


Buy Now for $42.00

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Related Articles
Journal Club
Related Point of Care
Topic Collections
PubMed Articles
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.