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Prevalence of Cholelithiasis in Idiopathic Late-Onset Immunoglobulin Deficiency

JOSE A. DIAZ-BUXO, M.D.; PAUL E. HERMANS, M.D., F.A.C.P.; and LILA R. ELVEBACK, Ph.D.
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▸Address reprint requests to Dr. J. A. Diaz-Buxo, Mayo Clinic, 200 First Street SW, Rochester, MN 55901.


Rochester, Minnesota


Ann Intern Med. 1975;82(2):213-214. doi:10.7326/0003-4819-82-2-213
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Twelve of 50 consecutive patients with idiopathic late-onset immunoglobulin deficiency had cholelithiasis. This represents a prevalence rate of 24%, which is significantly above the rate in a control group of 500 patients from this medical center matched 10:1 for age and sex (P < 0.005). This finding adds a new gastrointestinal abnormality to those known to occur in idiopathic late-onset immunoglobulin deficiency.

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