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Low Blood Pressure in Young Adults with Cystic Fibrosis: An Effect of Chronic Salt Loss in Sweat?

JACK LIEBERMAN, M.D., F.A.C.P.; and SIMON RODBARD, M.D., F.A.C.P.
[+] Article and Author Information

Grant support: grant HL13398, National Institutes of Health, and in part by the Helen Galland Research Fund.

▸Requests for reprints should be addressed to Jack Lieberman, M.D., City of Hope Medical Center, 1500 E. Duarte Road, Duarte, CA 91010.


Duarte, California


Ann Intern Med. 1975;82(6):806-808. doi:10.7326/0003-4819-82-6-806
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Young adults with cystic fibrosis have lower blood pressures than control subjects of similar age and sex. The low blood pressure may be related to the excessive loss of salt in the sweat of these patients. A beneficial effect of the cystic fibrosis gene may be protection against developing hypertension in both the homozygous and heterozygous states, especially if the heterozygote has borderline elevation of sweat electrolytes.

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