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Long-Term Therapy of Urinary Tract Infections

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Veterans Administration Hospital, Madison, Wisconsin

Ann Intern Med. 1975;83(2):273-274. doi:10.7326/0003-4819-83-2-273
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A general consensus about treatment of urinary tract infections has begun to emerge over the past 20 years. Clearly, the concepts established by Kass in 1955 (1) that define the principles of chemotherapy have stood the test of time. The most important factors affecting both the initial and long-term prognosis are the presence of underlying structural or neurologic lesions that interfere with the voiding mechanism. Included here are foreign bodies such as renal, bladder, or prostatic calculi and catheters.

The urinary tract is almost ideally suited to respond to chemotherapy. Relatively high levels of drug may be concentrated in the


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