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Crohn's Disease of the Mouth

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University of Chicago, Chicago, Illinois

Ann Intern Med. 1975;83(4):570-571. doi:10.7326/0003-4819-83-4-570
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Crohn's disease was first observed in the terminal ileum, but has since been shown capable of involving any part of the gastrointestinal tract from the mouth to the anus. It is well known that anal lesions ultimately appear in the majority of patients, but what of the oral lesions? How frequently do they occur? What are their characteristics? In what clinical setting do these lesions develop? Are there special therapeutic considerations?

The first report of Crohn's disease of the mouth was not published until 1969, and only an additional 14 case reports had appeared through 1974. Although Croft and Wilkinson


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