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Renal Transplantation in Multiple Myeloma: A Case Report

RICHARD L. HUMPHREY, M.D.; JOHN R. WRIGHT, M.D.; JIMMY B. ZACHARY, M.D.; SYLVESTER STERIOFF, M.D.; and RALPH A. DeFRONZO
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▸Requests for reprints should be addressed to Richard L. Humphrey, M.D., The Johns Hopkins University Oncology Center, Carnegie 322, Baltimore, MD 21205.


Baltimore, Maryland


Ann Intern Med. 1975;83(5):651-653. doi:10.7326/0003-4819-83-5-651
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A patient with plasma cell myeloma presented in severe renal failure but was otherwise considered a good risk candidate for chemotherapy. Supported by hemodialysis she received intensive cyclophosphamide chemotherapy, resulting in a stabilization of all overt manifestations of her disease except for the renal failure. After 11½ months of follow-up without showing any further progression of the myeloma process, she received a successful cadaveric renal transplant, which functioned well until the time of her death 15 months later. No evidence of recurrent myeloma kidney disease was found at postmortem examination.

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