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Bacterial Endocarditis Caused by Oerskovia turbata

L. BARTH RELLER, M.D., F.A.C.P.; GERRY L. MADDOUX, M.D.; MARK R. ECKMAN, M.D.; and GEORGE PAPPAS, M.D.
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Presented in part on 2 May 1975 at the 75th Annual Meeting of the American Society for Microbiology, New York, New York.

▸Requests for reprints should be addressed to L. Barth Reller, M.D., Box B168, University of Colorado Medical Center, 4200 East 9th Avenue, Denver, CO 80220.


Denver, Colorado


Ann Intern Med. 1975;83(5):664-666. doi:10.7326/0003-4819-83-5-664
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Oerskovia turbata is a yellow, motile actinomycete, which before now has only been found in soil and has not been known to cause disease in man or animals. It was isolated from 29 cultures of blood taken during 6 months from an urban pensioner after homograft replacement of his aortic valve. The combination of ampicillin, sulfamethoxazole, and trimethoprim was lethal for O. turbata in vitro; however, antimicrobial therapy alone failed to eradicate the patient's infection. Cure was achieved after the infected homograft was replaced with a prosthetic aortic valve. Although the source of O. turbata in this patient is unknown, sterilization of homograft valves with antimicrobial solutions is difficult. Moreover, environmental contamination during cardiopulmonary bypass is common. Oerskovia turbata is another opportunistic pathogen of man.

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