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Pulmonary Radiation Reactions

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Department of Radiation Therapy
Arnot-Ogden Memorial Hospital
Roe Avenue
Elmira, New York 14901

Ann Intern Med. 1975;83(5):738. doi:10.7326/0003-4819-83-5-738_2
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To the editor: I have recently described the appearance of increased clinically symptomatic pulmonary radiation reactions with adjuvant chemotherapy (1), specifically a combination of nitrogen mustard, procarbazine, and vincristine. My comments in that paper suggested that "increased reactions be looked for in all organ systems that are irradiated during combination studies." Further evidence in support of this statement is given by the recent report of synergistic cardiotoxicity with adriamycin and radiation in your journal by Merrill and associates (Ann Intern Med 82:122-123, 1975), and another article by Cassady and associates (2) on treatment of Wilms tumor with combined modality therapy.


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