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Defective Triglyceride Removal in Lipemia Associated with Peritoneal Dialysis and Haemodialysis

D. C. CATTRAN, M.D., F.R.C.P.(C); S. S. A. FENTON, M.D., M.R.C.P.(I); D. R. WILSON, M.D., F.R.C.P.(C); and G. STEINER, M.D., F.R.C.P.(C)
[+] Article, Author, and Disclosure Information

Grant Support: Medical Research Council MT2 834.

Presented in part April 1974 at the American Society of Artificial Internal Organs, Chicago, 8 April 1974.

▸Requests for reprints should be addressed to D. C. Cattran, M.D.; Room 3200, College Wing, Toronto General Hospital; Toronto, Ontario, Canada, M5G 1L7.

Toronto, Ontario,Canada

Ann Intern Med. 1976;85(1):29-33. doi:10.7326/0003-4819-85-1-29
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Plasma lipids were measured in 78 uremic patients receiving either chronic peritoneal dialysis or haemodialysis. Type IV hyperlipemia was found in 60% of patients. The lipid level was not influenced by dietary habits or patient's age. Patients on chronic peritoneal dialysis had a significantly higher and more sustained hyperlipemia than the patients on haemodialysis.Triglyceride turnover studies showed that all patients, regardless of the type of dialysis or lipid level, had impaired triglyceride removal as the cause of this lipemia. This defect in triglyceride metabolism was only partially corrected by increasing the efficiency of the dialysis.





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