0

The full content of Annals is available to subscribers

Subscribe/Learn More  >
Articles |

Sites of Conduction Disease in Aortic Stenosis: Significance of Valve Gradient and Calcification

RAMESH C. DHINGRA, M.D., F.A.C.P.; FERNANDO AMAT-y-LEON, M.D.; RAYMOND J. PIETRAS, M.D., F.A.C.P.; CHRISTOPHER WYNDHAM, M.D.; PRAKASH C. DEEDWANIA, M.D.; DELON WU, M.D.; PABLO DENES, M.D.; and KENNETH M. ROSEN, M.D.
[+] Article and Author Information

Grant support: in part by NIH Grant HL18794-02, U.S. Public Health Service Training Grant HL-05879-07, and Basic Institutional Support, MRIS No. 1828, West Side Veterans Administration Hospital; Chicago, Illinois.

▸Requests for reprints should be addressed to Ramesh C. Dhingra, M.D.; Cardiology Section, University of Illinois Hospital; P.O. Box 6998; Chicago, IL 60680.


Chicago, Illinois


Ann Intern Med. 1977;87(3):275-280. doi:10.7326/0003-4819-87-3-275
Text Size: A A A

Electrophysiologic studies were done in 32 patients with aortic stenosis. In 24 patients with intact A-V conduction, A-H intervals ranged from 55 to 145 msec and were prolonged in two. Two had split His bundle potentials. The H-V intervals ranged from 25 to 94 msec and were prolonged in 12. The mean H-V interval was 63 ± 2.6 msec in 12 patients with calcific aortic stenosis compared with 50 ± 4.9 msec in 12 without calcification (P < 0.05). The mean H-V in 10 patients with aortic gradients > 40 mm Hg was 62 ± 5.6 msec compared with 47 ± 3.1 msec in nine with gradients < 40 (P < 0.05). In patients with aortic stenosis and A-V block, the site of the block was distal to the His bundle in three and within the His bundle in five. All eight had calcified valves. Aortic stenosis was commonly associated with latent and manifest conduction disease in the His bundle and the trifascicular conduction system. Conduction disease was more extensive with calcified valves and greater valve obstruction.

Figures

Tables

References

Letters

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Comments

Submit a Comment
Submit a Comment

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.

Toolkit

Buy Now

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Advertisement
Related Articles
Topic Collections
PubMed Articles

Buy Now

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.
(Required)
(Required)