The full content of Annals is available to subscribers

Subscribe/Learn More  >
Brief Communications |

Phenformin and Hyperamylasemia in Lactic Acidosis

[+] Article, Author, and Disclosure Information

▸Requests for reprints should be addressed to Joseph E. Loewenstein, M.D., F.A.C.P.; Chief, Section of Endocrinology, Louisiana State University Medical Center; P.O. Box 33932; Shreveport, LA 71130.

Ann Intern Med. 1977;87(3):312-313. doi:10.7326/0003-4819-87-3-312
Text Size: A A A

All cases of lactic acidosis occurring during a 23-month period in a metropolitan teaching hospital were reviewed to ascertain the frequency of hyperamylasemia. Serum amylase activity had been measured in 12 of 26 patients and was elevated in eight (67%). Hyperamylasemia was not significantly more frequent in patients with phenformin-associated lactic acidosis than in patients with lactic acidosis who had not received phenformin. Serum amylase activity did not correlate with the severity of acidosis (arterial pH) or with renal function (serum creatinine).





Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Submit a Comment/Letter
Submit a Comment/Letter

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.


Buy Now for $42.00

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Related Articles
Journal Club
Topic Collections
PubMed Articles
Phenformin and hyperamylasemia in lactic acidosis. Ann Intern Med 1977;87(3):312-3.
[Lactic acidosis, hyperamylasemia, and phenformin]. Minerva Med 1992;83(12):777-83.
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.