The full content of Annals is available to subscribers

Subscribe/Learn More  >
Original Research |

Intravenous Elemental Mercury Injection: Blood Levels and Excretion of Mercury

[+] Article, Author, and Disclosure Information

▸Requests for reprints should be addressed to John Ambre, M.D., Ph.D.; Department of Internal Medicine, University of Iowa Hospitals and Clinics; Iowa City, IA 52242.

Iowa City, Iowa

Ann Intern Med. 1977;87(4):451-453. doi:10.7326/0003-4819-87-4-451
Text Size: A A A

The blood level and excretion of mercury was measured in a patient who injected 1 ml (13.6 g) of elemental mercury intravenously. The chest radiograph showed metallic densities delineating small pulmonary vessels. The patient had no signs or symptoms of mercury intoxication in the year after injection. Mercury blood levels were essentially constant, averaging 62 ng/ml. Although exhalation of mercury vapor was a major route of excretion and urinary mercury rose fivefold with administration of penicillamine, excretion by all routes, estimated for the year after injection, represented only 1% of the dose. Total body clearance of mercury was only 5 ml/min. Penicillamine therefore appeared to be of little value in reducing the body burden of mercury. The data also suggest that acute systemic mercury intoxication is unlikely after intravascular elemental mercury injection because blood mercury levels are low.





Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Submit a Comment/Letter
Submit a Comment/Letter

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.


Buy Now for $42.00

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Related Articles
Topic Collections
PubMed Articles
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.