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Amyloidosis in a Renal Allograft in Familial Mediterranean Fever

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Department of Internal Medicine
University of Nebraska Medical Center
Omaha, NB 68105

Ann Intern Med. 1977;87(5):579-580. doi:10.7326/0003-4819-87-5-579
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The most common cause of death in familial Mediterranean fever is renal failure secondary to amyloidosis (1). Despite the occurrence of extrarenal amyloidosis in patients with this disease, failure of other organs is uncommon (1). At least four patients have been treated with transplantation for renal failure, and no recurrence of amyloidosis has been reported in these allograft kidneys (2-5). (While this paper was in press, a similar report appeared: Benson MD, Skinner M, Cohen AS: Amyloid deposition in renal transplant in familal Mediterranean fever. Ann Intern Med 87:31-34, 1977.)

A patient with familial Mediterranean fever who received an allograft


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