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Hypercalcemia and Idiopathic Hypertrophic Subaortic Stenosis

KAY F. MCFARLAND, M.D., F.A.C.P.; MILTIADIS A. STEFADOUROS, M.D.; ABDULLA M. ABDULLA, M.D.; and DEE E. MCFARLAND, M.D.
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Department of Medicine
Medical College of Georgia
Augusta, GA 30902


Ann Intern Med. 1978;88(1):57-58. doi:10.7326/0003-4819-88-1-57
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Although the primary cause of idiopathic hypertrophic subaortic stenosis is not known, it has been suggested that this cardiomyopathy may be induced by continuous excessive positive inotropic stimulation of the myocardium (1). Because calcium is known to have a positive inotropic effect on the heart, the present study was designed to ascertain the prevalence of hypercalcemia in patients with idiopathic hypertrophic subaortic stenosis.

Idiopathic hypertrophic subaortic stenosis was documented in 31 patients at the Eugene Talmadge Memorial Hospital during 1972-1977. In 29 patients, the diagnosis was made from the left ventricular (LV) angiogram using standard criteria (2) and supported in

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