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Determination of Mitral Valve Area by Cross-Sectional Echocardiography

L. S. WANN, M.D.; ARTHUR E. WEYMAN, M.D.; HARVEY FEIGENBAUM, M.D.; JAMES C. DILLON, M.D.; K. W. JOHNSTON, B.S.; and REGINALD C. EGGLETON, M.S.
[+] Article and Author Information

▸Requests for reprints should be addressed to L.S. Wann, M.D.; Cardiology Section, Veterans Administration Hospital, 1481 W. 10th St.; Indianapolis, IN 46202.


Indianapolis, Indiana


© 1978 American College of PhysiciansAmerican College of Physicians


Ann Intern Med. 1978;88(3):337-341. doi:10.7326/0003-4819-88-3-337
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Cross-sectional echocardiograms of the mitral valve orifice were recorded in 37 patients with mitral stenosis. Twenty-seven had pure mitral stenosis, and 10 had associated mitral regurgitation. Mitral valve area in patients with pure mitral stenosis measured from cross-sectional echocardiography was highly correlated (r = 0.89) with that calculated with the Gorlin formula using the pressure gradient and Fick cardiac output. With mitral regurgitation, mitral valve area by cross-sectional echocardiography correlated well (r = 0.90) with that calculated from the pressure gradient and cineangiographic stroke output. In two cases, direct pathologic measurements of mitral valve area agreed exactly with the cross-sectional echocardiographic measurement. Correlation between the mitral E-F slope and mitral valve area by cross-sectional echocardiography (r = 0.56) and catheterization (r = 0.49) was less reliable. Cross-sectional echocardiographic measurement of the mitral valve area correlates well with catheterization in patients with pure mitral stenosis and those with associated regurgitation.

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