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T3 Euthyroidism in Follicular Thyroid Carcinoma

Ann Intern Med. 1978;88(3):359-360. doi:10.7326/0003-4819-88-3-359
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Follicular thyroid carcinoma comprises about 25% of all thyroid cancers, and its malignancy generally exceeds that of papillary carcinoma. It spreads relatively early to distant sites such as bone, lungs, and liver by invasion of blood vessels, and regional lymph nodes are usually involved only late. Production of thyroid hormones is almost exclusively associated with the follicular histologic type. In many reported cases the production of thyroid hormones by metastases has been sufficient to cause hyperthyroidism. One of these cases was that of a patient with "T3 thyrotoxicosis" (1).

We describe here a patient having metastatic follicular thyroid carcinoma with


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