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Therapy for Multifactorial Hypertension

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Research Division, The Cleveland Clinic Foundation, Cleveland, Ohio

Ann Intern Med. 1978;88(5):705-706. doi:10.7326/0003-4819-88-5-705
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The distance from therapeutic nihilism to aggressive mobilization of socioeconomic resources against hypertension has been covered in only a few years. It was not long ago that some were still arguing that hypertension might be a compensatory mechanism and better left untouched. We have come a long way, but we should not forget how we came lest we go from one excess into another.

Of the many concepts that evolved from the extensive work in hypertension, few have proved as durable or productive as the mosaic theory of Page (1, 2). The complex of hemodynamic, humoral, volume, and neurogenic factors




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