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Parathyroid Adenoma and Previous Head-and-Neck Irradiation

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The Fairfax Hospital, Falls Church, Virginia

© 1978 American College of PhysiciansAmerican College of Physicians

Ann Intern Med. 1978;88(6):804. doi:10.7326/0003-4819-88-6-804_1
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The association of tumors of the head and neck with previous radiation exposure has been well documented. Both benign and malignant neoplasms of the thyroid, brain, larynx, facial bones, scalp, and salivary glands have been reported after various latency periods.

We describe here two cases of hyperfunctioning parathyroid adenoma and relate their genesis to previous radiation therapy directed to the head and neck.

A 48-year-old white man with hypertension since the age of 20 had been treated recently with Rauwolfia derivatives but at one time had taken hydrochlorothiazide. About 1 year before his admission a routine chemical screen in another


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