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Spontaneous Remission from Primary Hypothyroidism

Ann Intern Med. 1978;88(6):808-809. doi:10.7326/0003-4819-88-6-808
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Primary hypothyroidism in adults has been thought to be an end-result of the destructive process of chronic thyroiditis (1, 2), for which life-long replacement therapy with desiccated thyroid or its equivalent has been an accepted method of treatment. In a recent issue of this journal, Amino and associates (3) described their experience with transient hypothyroidism, which they observed in 14 postpartum women. We found a young woman spontaneously recovered from hypothyroidism accompanied by goiter, which was not associated with pregnancy.

A 24-year-old woman had been well until April 1976, when she noticed easy fatigability and swelling of a few cervical


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