Among the many neurologic complications of the uremic syndrome, abnormalities of behavior and cerebral function are usually discernible early. Fatigue, lethargy, irritability, recent memory loss, and inability to concentrate are commonly recognized. Severe renal failure may result in disorientation, confusion, global memory failure, euphoria, depression, seizures, hallucinations, or acute psychosis (1).
Catatonia as a manifestation of uremia has rarely been mentioned in the literature (2) and never before described in detail. The two patients in this report had prominent catatonic stupor as the major neurologic finding associated with uremia. Catatonia resolved rapidly and completely in both patients with dialysis.