0

The full content of Annals is available to subscribers

Subscribe/Learn More  >
Brief Communications |

Acromegaly and Galactorrhea-Amenorrhea with Two Pituitary Adenomas Secreting Growth Hormone or Prolactin: A Case Report

GEORGE TOLIS, F.R.C.P.(Gr); GILLES BERTRAND, F.R.C.P.(C); STIRLING CARPENTER, F.R.C.P.(C); and JOHN MAXWELL McKENZIE, F.R.C.P.(E)
[+] Article and Author Information

▸Requests for reprints should be addressed to George Tolis, M.D., F.R.C.P. (Gr); Division of Endocrinology and Metabolism, Royal Victoria Hospital; 687 Pine Avenue West; Montreal, PQ, Canada H3A 1A1.


Montreal, Quebec, Canada


© 1978 American College of PhysiciansAmerican College of Physicians


Ann Intern Med. 1978;89(3):345-348. doi:10.7326/0003-4819-89-3-345
Text Size: A A A

A prolactinoma was removed from a nulliparous woman who had acromegaly, galactorrhea-amenorrhea, elevated serum growth hormone and prolactin, and hypogonadotropinism. Postoperatively galactorrhea decreased and cyclic vaginal bleeding ensued; serum prolactin concentration was normal but growth hormone remained elevated and the acromegalic complex was unchanged, even after subsequently administered bromocriptine. At a second transsphenoidal operation, an adenoma of somatotropes was removed; improvement in symptoms and signs and normalisation of pituitary function, including growth hormone, followed. The possible presence of distinctly separate pituitary adenomas should be considered in patients with galactorrhea associated with acromegaly.

Figures

Tables

References

Letters

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Comments

Submit a Comment
Submit a Comment

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.

Toolkit

Buy Now

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Advertisement
Related Articles
Related Point of Care
Topic Collections
PubMed Articles
Pituitary macroadenoma presenting as a nasal tumor: case report. Sao Paulo Med J Published online Aug 22, 2014.;
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.
(Required)
(Required)