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Carcinoid of the Thymus with Hereditary Hyperparathyroidism

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This study was supported in part by National Cancer Institute Grant C 1560.

Ann Intern Med. 1978;89(3):364-365. doi:10.7326/0003-4819-89-3-364
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Primary carcinoid tumor of the thymus was first described in detail by Rosai and Higa in 1972, and at least 24 patients with the disease have been reported to date (1-7). A few of the patients had additional features of multiple endocrine neoplasia type I, with hyperplasia or neoplasia of pancreatic islet cells, and parathyroid, pituitary, adrenal, or thyroid glands (2, 3). This case report describes a patient with carcinoid of the thymus associated with hereditary hyperparathyroidism.

The propositus was in good health until 44 years of age in 1971 when a routine examination showed a 10-cm mediastinal mass in


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