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IV. Problems in the Use of Antibiotics |

Hospital Use of Antimicrobial Drugs: Survey at 19 Hospitals and Results of Antimicrobial Control Program

WILLIAM A. CRAIG, M.D.; STEPHEN J. UMAN, M.D.; WILLIAM R. SHAW, M.D.; VADAKEPAT RAMGOPAL, M.D.; LLOYD L. EAGAN, M.S.; and E. THEMIS LEOPOLD, B.S.
[+] Article and Author Information

▸Requests for reprints should be addressed to William A. Craig, M.D.; Infectious Disease Section, William S. Middleton Memorial Veterans Administration Hospital; Madison, WI 53705.


Madison, Wisconsin


© 1978 American College of PhysiciansAmerican College of Physicians


Ann Intern Med. 1978;89(5_Part_2):793-795. doi:10.7326/0003-4819-89-5-793
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Costs and use of antimicrobial agents in 1976 at 19 hospitals were surveyed by review of pharmacy records. Total costs of antimicrobial drugs at individual hospitals ranged from $0.65 to $1.75 per patient day and accounted for 16% to 41% of total pharmacy drug costs. There was marked variation among hospitals in use of specific antimicrobial agents, especially cephalosporins and clindamycin. The cephalosporin and aminoglycoside antibiotics accounted for 66% of the total cost of antimicrobial agents. An 18-month antimicrobial drug control program at one hospital decreased antimicrobial drug costs by 31%. The major effect was in reducing cephalosporin use. The results of the control program document that a significant portion of hospital antimicrobial use is inappropriate and can be eliminated without apparent detriment to patient care.

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