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Cerebral Lupus Erythematosus

Ann Intern Med. 1979;90(3):430-431. doi:10.7326/0003-4819-90-3-430
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Surveys of the pattern of systemic lupus erythematosus and its involvement of the central nervous system undoubtedly show changing characteristics. There have been two noticeable trends: The overall prognosis has improved, and more patients show evidence that the central nervous system is involved—-roughly two thirds of patients studied (1). The commonest presentation of involvement of the central nervous system is psychiatric illness ranging from mild affective disorder to full-blown psychosis. What looms larger than ever in management of systemic lupus erythematosus is the difficulty in recognizing lesions of the central nervous system clinically manifest by psychosis but including manifestations as


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