0

The full content of Annals is available to subscribers

Subscribe/Learn More  >
Brief Communications |

Neisseria meningitidis and Neisseria gonorrhoeae Bacteremia Associated with C6, C7, or C8 Deficiency

BRUCE H. PETERSEN, Ph.D.; TERRENCE J. LEE, M.D.; RALPH SNYDERMAN, M.D.; and GEO. F. BROOKS, M.D.
[+] Article and Author Information

This study was supported by grants AI 13927, AI 15642, and AI 15036 from the National Institute of Allergy and Infectious Diseases and DE 03738-05 from the National Institute for Dental Research. Dr. Snyderman is an investigator of the Howard Hughes Medical Institute.

▸Requests for reprints should be addressed to Bruce H. Petersen, Ph.D.; Lilly Laboratory for Clinical Research, Wishard Memorial Hospital, 1001 West 10th Street; Indianapolis, IN 46202.


Indianapolis, Indiana; Chapel Hill and Durham, North Carolina; and San Francisco, California


© 1979 American College of PhysiciansAmerican College of Physicians


Ann Intern Med. 1979;90(6):917-920. doi:10.7326/0003-4819-90-6-917
Text Size: A A A

We summarize data from 24 previously described or newly diagnosed cases of homozygous deficiency of the sixth, seventh, or eighth components of complement. Thirteen of 24 patients had at least one episode, and usually two or more episodes of Neisseria meningitidis or Neisseria gonorrhoeae bacteremia, or both. Deficiency of C6, C7, or C8 is a meaningful risk factor for repeated neisserial bacteremia; conversely, hemolytic complement studies are indicated in patients who develop recurrent neisserial infections. When a person with C6, C7, or C8 deficiency is identified, family members should also be studied.

Figures

Tables

References

Letters

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Comments

Submit a Comment
Submit a Comment

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.

Toolkit

Buy Now

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Advertisement
Related Articles
Journal Club
Related Point of Care
Topic Collections
PubMed Articles
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.
(Required)
(Required)