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Possible Nosocomial Transmission of Group Y Neisseria meningitidis Among Oncology Patients

MYRON S. COHEN, M.D.; ALLEN C. STEERE, M.D.; ROBERT BALTIMORE, M.D.; ALEXANDER von GRAEVENITZ, M.D.; ELIZABETH PANTELICK, R.N., M.P.H.; BURDEEN CAMP, P.A.; and RICHARD K. ROOT, M.D.
[+] Article and Author Information

Parts of this work have appeared in abstract form (45, 46).

▸Requests for reprints should be addressed to Allen C. Steere, M.D.; Department of Internal Medicine, Yale University School of Medicine; 333 Cedar Street; New Haven CT 06510.


New Haven, Connecticut


© 1979 American College of PhysiciansAmerican College of Physicians


Ann Intern Med. 1979;91(1):7-12. doi:10.7326/0003-4819-91-1-7
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Within 4 days, two oncology patients in the Clinical Research Unit had bacteremia caused by group Y Neisseria meningitidis. Three additional patients, identified by prevalence survey, were found to have nasopharyngeal colonization with that serogroup, compared with only one employee (not associated with patients) and no family contacts. Infected and colonized (case) patients were located in the same or adjacent rooms but did not have close contact. A comparison of host and risk factors showed no significant differences between case patients and the other (control) patients located in the same rooms. In retrospect, the index patient, who had marked sputum production but was not isolated, had unrecognized meningococcal pneumonia and probably was the hospital source of a heavy, airborne dispersal of organisms to other patients. Respiratory isolation is warranted for patients with suspected N. meningitidis infection.

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