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Aortic Stenosis and Mucopolysaccharidosis

CHARLES S. WILSON, M.D.; HAROLD T. MANKIN, M.D.; and JAMES R. PLUTH, M.D.
[+] Article and Author Information

▸Requests for reprints should be addressed to Harold T. Mankin, M.D.; Mayo Clinic, 200 First Street, SW; Rochester, MN 55901.


Rochester, Minnesota


© 1980 American College of PhysiciansAmerican College of Physicians


Ann Intern Med. 1980;92(4):496-498. doi:10.7326/0003-4819-92-4-496
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A 43-year-old man had severe aortic stenosis and Maroteaux-Lamy syndrome (mucopolysaccharidosis, type VI). Aortic-valve replacement gave a good long-term result. Information was obtained indicating that his two brothers had also had mucopolysaccharidosis and aortic stenosis and that both had died of cardiac disease. This paper reviews the literature on cardiac involvement in mucopolysaccharidosis.

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