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Concurrent Respiratory Syncytial Virus and Influenza A Infections in the Institutionalized Elderly and Chronically III

USHA MATHUR, M. D.; DAVID W. BENTLEY, M.D.; and CAROLINE B. HALL, M.D.
[+] Article and Author Information

Grant support: by a contract (N01-AI-22503) from the Development and Application Branch, Microbiology and Infectious Disease Program, National Institute of Allergy and Infectious Disease.

This paper was presented in part at the 18th Interscience Conference on Antimicrobial Agents and Chemotherapy, Atlanta, Georgia, 1-4 October 1978.

▸Requests for reprints should be addressed to David W. Bentley, M.D.; Infectious Disease Unit, Monroe Community Hospital, 435 East Henrietta Road; Rochester, NY 14603.


Rochester, New York


© 1980 American College of PhysiciansAmerican College of Physicians


Ann Intern Med. 1980;93(1_Part_1):49-52. doi:10.7326/0003-4819-93-1-49
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During a community outbreak of respiratory syncytial virus and influenza A/Texas/77 infections, we investigated 71 cases of upper respiratory illness at a chronic disease hospital using a surveillance system plus viral and serologic studies. Of the 32 patients with an etiologic diagnosis, seven had respiratory syncytial virus, 24 had influenza, and one had dual infections with respiratory syncytial virus and influenza. No definite etiologic diagnosis was made in the remaining 39 patients. A comparison of the clinical features of patients infected with respiratory syncytial virus and influenza revealed no significant differences in the frequency of respiratory or constitutional signs and symptoms except for rhinorrhea, which was commoner in the respiratory syncytial virus group (P < 0.05). Pneumonia developed in one patient with respiratory syncytial virus and in five patients with influenza. Our findings suggest that respiratory syncytial virus may be an important respiratory pathogen for the elderly and chronically ill, causing illness similar to influenza.

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