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Stone Disease in Hereditary Distal Renal Tubular Acidosis

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Michael Reese Hospital and the University of Chicago; Chicago, Illinois

Ann Intern Med. 1980;93(1_Part_1):60-61. doi:10.7326/0003-4819-93-1-60
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The stone disease produced by hereditary distal renal tubular acidosis (1,2) has been described mainly in case reports (3-12), but only rarely in detail (12). We have treated six patients for 7 to 19 years. We quantify here the frequency of new stone formation as well as the morbidity produced by stones before and during treatment of these six patients.

Four of the patients belong to one family (Table 1, Patients 1 through 4); the other two are unrelated to one another. All six had hyperchloremic acidosis and calcium renal stones and could not lower their urine pH below 6.0


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