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Corticosteroid-Responsive Hypercalcemia with Elevated Serum 1-Alpha, 25 Dihydroxyvitamin D

BOY FRAME, M.D.; and A. M. PARFITT, M.B., B.Chir.
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This paper was presented in part at the Fourth International Workshop on Vitamin D, West Berlin, Germany, 18-22 February 1979.

▸ Requests for reprints should be addressed to Boy Frame, M.D.; Henry Ford Hospital, 2799 West Grand Boulevard; Detroit, MI 48202.

© 1980 American College of PhysiciansAmerican College of Physicians

Ann Intern Med. 1980;93(3):449-451. doi:10.7326/0003-4819-93-3-449
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A 51-year-old man has had absorptive hypercalciuria and corticosteroid-responsive hypercalcemia for at least 12 years. There has been no clinical or laboratory proof of primary hyperparathyroidism, hypervitaminosis D, or other known causes of hypercalcemia and absorptive hypercalciuria. Hypercalciuria as well as the elevated serum level of calcium and 1 α, 25(OH)2D fell to normal during treatment with corticosteroids. The disturbed calcium metabolism in this patient is characteristic of that observed in sarcoidosis, but extensive studies have failed to uncover evidence of this condition.





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