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Postsplenectomy Sepsis with DF-2: Report of a Case with Isolation of the Organism from the Patient's Dog

WILLIAM J. MARTONE, M.D.; RICHARD W. ZUEHL, M.D.; GEORGE E. MINSON, M.D.; and W. MICHAEL SCHELD, M.D.
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Use of trade names is for identification only and does not imply endorsement by the Public Health Service of the U.S. Department of Health and Human Services.


University of Virginia Medical Center; Charlottesville, Virginia; and the Center for Disease Control; Atlanta, Georgia


Ann Intern Med. 1980;93(3):457-458. doi:10.7326/0003-4819-93-3-457
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This excerpt has been provided in the absence of an abstract.

A fastidious gram-negative bacillus, operationally referred to as DF-2 at the Center for Disease Control, has recently been described as causing human bloodstream infections and meningitis (1-4). Butler and associates (2) found that 10 of 17 persons with DF-2 infection had been bitten by dogs, suggesting a zoonotic reservoir.

The following case represents the first time to our knowledge that DF-2 has been isolated from the pet dog implicated in the transmission of infection.

A 44-year-old man underwent a staging laparotomy with splenectomy in November 1977 for Hodgkin's disease. He subsequently received chemotherapy and radiotherapy. The patient remained well until

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