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Vitamin A Deficiency from Long-Term Parenteral Nutrition

LYN HOWARD, M.B.; RICHARD CHU, Ph.D.; STEPHEN FEMAN, M.D.; HOWARD MINTZ, B.A.; LARS OVESEN, M.D.; and BRUCE WOLF, M.S.
[+] Article and Author Information

Supported by grant 1-MO-1-RR-00749-04 from the General Clinical Research Center, grant 17767-03 from the U.S. Public Health Service, and grant 5901-0410-9-0297-0 from the U.S. Department of Agriculture.

▸Requests for reprints should be addressed to Lyn Howard, M.B.; Albany Medical College; Albany, NY 12208.


Albany Medical College and Veterans Administration Medical Center; Albany, New York. Vanderbilt University; Nashville, Tennessee


Ann Intern Med. 1980;93(4):576-577. doi:10.7326/0003-4819-93-4-576
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In the past 10 years some 500 Americans have been discharged home on self-administered parenteral nutrition (Registry of Patients on Home Parenteral Nutrition, New York Academy of Science, 2 East 103 Street, New York, NY 10029). In most of these patients the underlying gastrointestinal disorder is some form of extreme short bowel syndrome, such as Crohn's or mesenteric infarction (1). Most home parenteral nutrition patients experience rapid regain of weight and strength; septic complications are rare (2), and not infrequently these persons return to full-time work. Although the typical hospital intravenous nutrition patient is seriously ill with multiple metabolic disturbances,

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