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Agrobacterium radiobacter Prosthetic Valve Endocarditis

GARY R. PLOTKIN, M.D.
[+] Article and Author Information

▸Requests for reprints should be addressed to Gary R. Plotkin, M.D.; Department of Infectious Diseases, Geisinger Medical Center; Danville, PA 17821.


Geisinger Medical Center; Danville, Pennsylvania.


Ann Intern Med. 1980;93(6):840. doi:10.7326/0003-4819-93-6-839
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Aerobic, facultatively anaerobic, and obligately anaerobic gram-negative bacteria have been isolated from 10% to 40% of cases of prosthetic valve endocarditis. Such isolates have included Proteus, Escherichia coli, Serratia marcescens, Klebsiella pneumoniae, Enterobacter, Salmonella, Haemophilus, Achromobacter, Acinetobacter calcoaceticus, Alcaligenes faecalis, Actinobacillus actinomycetem-comitans, Eikenella corrodens, Brucella, Cardiobacterium hominis, Neisseria, and Bacteroides fragilis (1, 2). Described herein is the first reported case of prosthetic valve endocarditis caused by Agrobacterium radiobacter, a gram-negative soil bacterium. A 77-year-old chiropractor was hospitalized in March 1979 for evaluation of fever and weight loss. Blood cultures grew penicillin-sensitive Streptococcus bovis that was treated with 28 days of

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