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Pulse Therapy in Rheumatoid Arthritis

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Dr. Kammen received support from an Ohio Arthritis Care and Education Program Fellowship.

Division of Immunology, Department of Medicine, University of Cincinnati Medical Center; Cincinnati, Ohio

Ann Intern Med. 1981;94(1):128-129. doi:10.7326/0003-4819-94-1-128
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Chronic symptomatic diseases for which specific causes are not known and therefore for which we have no specific therapies are unfortunately still very much with us. This lack has resulted in the use of many forms of therapy that might offer a possibility of improving the quality or extent of life despite the absence of scientific evidence of efficacy and safety. This trend has resulted in use of a variety of medical fads that have fallen by the wayside. The use of high-dose oral steroids in the treatment of rheumatoid arthritis during the 1950s is a well-known example. The consequences


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