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Theophylline-Induced Urinary Retention

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▸Requests for reprints should be addressed to Gregory R. Owens, M.D.; 329 Falk Clinic, University of Pittsburgh, 3601 Fifth Avenue; Pittsburgh, PA 15213.

Hospital of the University of Pennsylvania and the Philadelphia College of Pharmacy and Science; Philadelphia, Pennsylvania

Ann Intern Med. 1981;94(2):212-213. doi:10.7326/0003-4819-94-2-212
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This excerpt has been provided in the absence of an abstract.

Theophylline is widely used in the therapy of patients with obstructive airways disease. Although numerous complications of therapy have been described (1), we are unaware of any reports of clinically significant effects of theophylline on the urinary tract. This report describes the cases of two patients with theophylline-induced urinary retention and reviews the experimental data supporting this association.

A 62-year-old man was hospitalized for cardiac surgery because of progressive angina. Review of systems showed a mildly decreased urinary stream and urinary hesitancy. His physical examination was significant only for a moderately enlarged prostate.

After receiving a successful coronary artery bypass


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