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Pneumocystis carinii Pneumonia: A Complication of Cushing's Syndrome

LOWELL B. ANTHONY, M.D.; and F. ANTHONY GRECO, M.D.
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▸Requests for reprints should be addressed to F. Anthony Greco, M.D.; Department of Medicine, Vanderbilt University School of Medicine; Nashville, TN 37232.


Vanderbilt University School of Medicine; Nashville, Tennessee


Ann Intern Med. 1981;94(4_Part_1):488-489. doi:10.7326/0003-4819-94-4-488
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Pneumocystis carinii pneumonia as a complication of steroid therapy in immunocompromised patients has been well documented (1-5). However, pneumocystis in the presence of endogenous hypercortisolism from Cushing's syndrome has not been previously reported. We report here a patient with Cushing's syndrome from bilateral adrenal hyperplasia in whom pneumocystis pneumonia developed.

A 24-year-old man was referred to Vanderbilt Hospital in September 1975 because of Cushing's syndrome unresponsive to pituitary radiation. The patient had been short and obese all his life and had gained 18.1 kg in the past 2 years. There had been a marked increase in his abdominal size and

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