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Aspiration Needle Biopsy of the Thyroid

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Division of Endocrinology and Metabolism, Toronto General Hospital; Toronto, Ontario, Canada

Ann Intern Med. 1981;94(4_Part_1):536-537. doi:10.7326/0003-4819-94-4-536
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Interest in a nonoperative diagnostic approach to thyroid nodules recently has been rekindled by the report of excessive thyroid neoplasms, both benign and malignant, found in a large number of patients who had received external radiation to the head and neck (1). Certain risk factors increase the suspicion of malignancy in a solitary thyroid nodule (2). First is a history of radiation; the risk of thyroid carcinoma is substantially increased by exposure to radiation, 25 to 30 years previously (3), estimates ranging from a two-fold to a one hundred-fold increase. The second factor is sex. All forms of thyroid disease


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